CD55 monoclonal antibody, clone MEM-118 (Biotin)
产品名称: CD55 monoclonal antibody, clone MEM-118 (Biotin)
英文名称: CD55 monoclonal antibody, clone MEM-118 (Biotin)
产品编号: MAB4642
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD55.
- Immunogen:
- Native purified CD55 from HPB-ALL human T cell line.
- Host:
- Mouse
- Theoretical MW (kDa):
- 60-70
- Reactivity:
- Human, Non-Human Primates
- Specificity:
- This antibody recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 KDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells; it is weakly present on NK cells.
- Form:
- Liquid
- Conjugation:
- Biotin
- Isotype:
- IgM
- Storage Buffer:
- In PBS, pH 7.4 (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Neurosteroids reduce inflammation after TBI through CD55 induction.
VanLandingham JW, Cekic M, Cutler S, Hoffman SW, Stein DG.Neurosci Lett. 2007 Sep 25;425(2):94-8. Epub 2007 Aug 25.
- 2.
- Structural and functional characterization of a novel T cell receptor co-regulatory protein complex, CD97-CD55.
Abbott RJ, Spendlove I, Roversi P, Fitzgibbon H, Knott V, Teriete P, McDonnell JM, Handford PA, Lea SM.J Biol Chem. 2007 Jul 27;282(30):22023-32. Epub 2007 Apr 20.
- 3.
- Decay-accelerating factor ameliorates systemic autoimmune disease in MRL/lpr mice via both complement-dependent and -independent mechanisms.
Miwa T, Maldonado MA, Zhou L, Yamada K, Gilkeson GS, Eisenberg RA, Song WC.Am J Pathol. 2007 Apr;170(4):1258-66.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 1604
- Gene Name:
- CD55
- Gene Alias:
- CR,CROM,DAF,TC
- Gene Description:
- CD55 molecule, decay accelerating factor for complement (Cromer blood group)
- Omim ID:
- 125240
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
- Other Designations:
- CD55 antigen,decay accelerating factor for complement
- Interactome
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